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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89384a9e17a306743bd0c64c32f6904154b27549041b0978324b1bd344093615' 
  AND token = 'ID2IowDrdqTpLzTKia3grnlZ5OPt1OAgv5/GvB0zYb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}