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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b275daa60b1cd7e333b53714e172da6383cc4954c74b0853a6b8e48a040e186' 
  AND token = '17ruOqXaSWFW0dxs0ZqJG/E/AXfFd7Nj2VYwId3LfQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}