SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5b1afc355d60a085861d0b25ca1046eab5428c8bb950693457159c76cafde40' 
  AND token = 'lruV2YD9pVWFOoCds/PzwbU48AdHb2DEkHYAinY/lzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}