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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '684a50dc292ec0dabfd5bafd6d7539df6cec2614cea05e0d5f6a296397940c65' 
  AND token = 'HdXoVTSbpBcfcTtttjpzTiBYdbk/MHFvG1KKDnamu50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}