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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fbc9cac94d04ed4e42913d635c4663dd36fc5fc9b58f56ffa36451771fba8c7' 
  AND token = 'u4tRYAV3QMHjIVmBU4YauGdALdmG+Cxh8uRwYaD3Zfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}