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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c84cff544072daad3984b2affd84da3c6d37a0e868c9c187c403fbff50ae902a' 
  AND token = 'YC3AV0QheCHOomFZ6+XiWmDGXWmC0w/ltxwYdSH84FY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}