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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2f5cfc92e7572a869784bf89b173b5bdd25a86a456951b4fc0da8c2fb073bf9' 
  AND token = 'JxKPA6boEmLziENMcrSEDGs21S2a1SRgAv0n9WjFFMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}