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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e0aac3f67f735d66f36b367fda08be4c83808beff68da9049eb11447314e293' 
  AND token = 'kSxZdzxoE/MnIXwnp4kCbO1xssa33CWe60n9Z481oE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}