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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d1b4dea6a1d431642e6107f24c09a24e361b909d3505bf4e417571010a40fb' 
  AND token = '7fiHYU8m/t2QQ8mqxAarzxueLMM6i6TWGdZvGOoP1io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}