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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e209f8b5ff23754af3b014ccfd810e65ab445fe221a75fda587d37f5ab4ed45d' 
  AND token = 'f5Lbxhtqsu/ESveDh+oqRbQRFILN2vYWGXHmiDt9GmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}