SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69f43f60e46eba6e157191c0144d5fcf98f9c782cebdf6832cdf0396bee58a7d' 
  AND token = 'sm3WhV+NYNTiLeoKAjQqTeIGewEHmGOd4aSwX113LRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}