SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c5ffba5104da0e41f4fd581d7abd6fe21350d77f3f75efa16909351c3c64d5d' 
  AND token = 'w0LTo21nr58U2BTU5aA6OcQQ//7FUvI4W3kTEFDiuY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}