SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bcb54a68d063bb0b51d6d05f2a5e8699e0c625157e9e967c9b30b93485d2e5c' 
  AND token = 'OybLA7qCkaFZM2QHhbc+dNPiCgkQrjK7Xjy3xm9EIXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}