SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a38747c85d9db2d5d3cf735c5f22b8907b2f0e2fc4faf44cfd8028f74778d62' 
  AND token = 'NcR5eBuQFCwRhhifKrN9y6iU4fdAXGCTSTVWzTHAOt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}