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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af414df327a5ee0051cdea9057ff502d8f910e0f02602de3ebf7428071b73653' 
  AND token = '48QSPnY6rhU6aWGyJxXYR+2wNQudaHUgmCQemm/vSTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}