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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da20b2693f09046e2a009fedd0b2c4057c2e8cd4d3e30b05e06b4c3cacae49d1' 
  AND token = 'S7pNTcF+co6X98i5hI/s10SLeaeFaJ1tuzzfaZ7yFzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}