SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0748a095ef29e2de0e3243672b39e73cf092eacb06e5d4261128f2a90b5eab6e' 
  AND token = 'RWe2gFxh+oTtqKQkM/qa6XI2CgGleo5PtusAT6eKFFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}