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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04f8e18376797d1bf848404c87c3f709ada5ab8c67ae4ca2dfe9653241a7a670' 
  AND token = 'S0o4eGJtSZkbHtQ/3/P5DviHnz2goHATJ0ROYjDMh+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}