SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6604478ddf8ef23376a675c0de1d20a1b38b4cdf8f077e1e387389c72544004e' 
  AND token = 'qYeyIjwNvSX7zpBq9ptHxNil+9X8jgDvLtTEdAvbDMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}