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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3590daf9375e2872163e49e921b05e4c2409d0925115db01bc2c83efa534d273' 
  AND token = '+G2TJYSywes6/bUCLmju8qtfmpENi389+YR+10ngIqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}