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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f3d93afc78bfe196a37be8a1ac45911ec42bd627e3b002eb109511c9d1d9e87' 
  AND token = 'BFB1qFBAkCTbW2/xxoxpO7lUqc9qcI8zEO9wwVzdjug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}