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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5795209b8e63bf0146d4a22cdbafba7456675ced80f7f999cca75e3b86cfb803' 
  AND token = 'w8A8JM9Ah0cWKCQm/BzeM8o/xuYAUBBd1sOW5FAb5P8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}