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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d510da78234be322043649c4418192f74156b51d4c1e7f1d7f4b4390d370c0' 
  AND token = 'OGhijqvtJfKbZd5JiEQUVNAo24BAsV7QZKDfsKsL2pA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}