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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3502414030e7f5427bd7f54c07c40be80fb75d0aafc6b56d54c3a6e1bbbbd9c4' 
  AND token = 'mkgFUFKKWa+8U7REAtiEkUgW913ecW8+8Q4tjsH6Oi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}