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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62c75447f736c859a7f32227baec61ef136785b1667bdd48f7d93c538aaf1b01' 
  AND token = 'TjIj+Pk+gP/HNi7uYaHKN0WoG0NzdHLTWoeZbj09//M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}