SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cb5c88ffc3fcadc914267caad38ff74dd2b388f0a9f4b00f2570c5e74b1e4cd' 
  AND token = 'J35YO+eF1gE2o9VBlXpoc7nF+31/WhTnsD9Y58vlI/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}