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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ee58aeb0d7ce8e7f130f56bf45b3b09bad6648bb374e6ce795a4863e36de452' 
  AND token = 'VBw/A/Dpj2saNQ4kfp9aAHlmejlnSHMEup81XXC1r7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}