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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7455a12d0d680793cfd713791b936f0d5d97a1fb7f7c7930d3c733d792244704' 
  AND token = 'zMP9UbE3w2ACgcWCtYntGdHQukD73BpxlmvsIMYMZL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}