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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15a102de6c62464a1b86f39bb3ec6f171dfad3446f1374f15106e130eec30c2e' 
  AND token = 'Jm/BdZNLG3+zlR+0+HKw4iF/0VQjFhRcFuNckvtcj2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}