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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dfde2db7efabb38c66a7536504308c3d33ff8209abaf59189a7ebad640b437a' 
  AND token = 'Bg22bbUVL6mU15D5Z4ceDmf3MMqYr+5LvKgpBbUsCZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}