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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2244ee48f8622a2451985e5ed2483ed77a5637306602dd6ddd888f37eeda3821' 
  AND token = '7SNCLXlk0H5FPJln8oJSwHz0vPYpG0BSHo3IQb7R+xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}