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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51e9920bdd5b2bad1d3167bcefe4fb25a90f5e940128790c4d1d4307c6059aa2' 
  AND token = 'eeE2S04xGt7Di+zx39a8iC8QfhTMNZg/MlPTSMlWaDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}