SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e249d7d3fc3ba01e6bdc1967452fb332ae5e22890b0d831cac26a86d37ec65a' 
  AND token = '7ysaIZgGGxSggv8SF+e/BbWxb4eCAr2ri1M8AoEvRdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}