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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81dd3b454b847e189a4103bddbc6d3d8ea0636bcc8e22e64ed70791830f3716f' 
  AND token = '60+XEMOXW1/AHN6Argmf5GnkcF7sDCUsxcBJMVSLysk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}