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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0edfa8f38eb47b7600396a8aa5beec21d4c82a2223967dad20d02bcb113f709f' 
  AND token = 'XHUl9Qwmb4012m1RJXgpo7VdMym4UlIvNUfvre6eP4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}