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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27a68834434f03ab48760d0bea6c1243b6f803a65a548dbc079e305e8b62fba1' 
  AND token = 'LeW38+e1kBXzfSAPXCEXiUwkqtyG+SgGUMGcozvx8TE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}