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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '300649f00cda6b7ca65800f6219203dd991b804381915dffc9b1dee5a0d973f5' 
  AND token = 'ETsNIse0leu6U4JPQ8vJyxiagJ/zhHTrIm4jf4a2UuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}