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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '401558fd63353c6ab80ee2acbf65f2eb7e374d1389f464ae8ce2241474355c67' 
  AND token = '38K+4+G4Vtp4XOR40koVric+/B1XwyN8pprjVrJQWZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}