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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e99e5c8a1bd2c509a7ff55a1541a0e94c0494a6782f121b5e11680b924bdd7cb' 
  AND token = 'Y61bgBXypUAut3Bq25FumJRybAXmxTnWIoG8wQ22ZUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}