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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c3d00dd002ec3e8565f72cf2b0a05dbfc2f62b6e95d3386a23b291def9f55cb' 
  AND token = 'ihZ+xy0PxU7G8hPlxV/klZTn/w5a8GexOaesYwqpGaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}