SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f759c25ec27d1c14c24de5a99983ae96df295790b1afb058bc975a82b30315bb' 
  AND token = 'TUf2D0V7Wc0F7ibn0AkYYvy6IbsAkHShzCOtgVFIYE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}