SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '884a9e13e6ff4ca1454fd4dfa06fe2435a5eecec3fefad9312dbafc816b9de01' 
  AND token = 'Ku2lVgEqZL2TSiuXDbUAbc7KU0UZiZk8iAaqhw7nqf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}