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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a5e656f69f27de7789e20ef4b78e45d503fa8e21126e423dec84d904f39c641' 
  AND token = 'hmQYxxOtK5hXlzNDTNyA2IfwzCtYbJ954fQMH2DQ0E8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}