SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be57bd54919cc81cf4da49dc37f141d0f5552fffc2ef4dc134ab695357cae824' 
  AND token = 'ZC6FiiNsD5a5pZQLET/9ZgbUB5d/h/9AzAetv2MkUgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}