SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7636690ae0766a6c5677212bbd49c840a365a527ee9ff81493219a77e1126edd' 
  AND token = 'p6eG+oG0UDu6rUP0CkA+DAdQujeyhLNVCtdyJK24XDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}