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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f18a1d7203c7699133239ab635310ce9cc6ac21d029d0cc5a726792f8eb93e' 
  AND token = 'tQqc5KKvF19v9pe2ogXoNE4ThKXl7moLpZiPtaAOyr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}