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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53c5dee3418153784df7cea6604564e89d3be0bba9a26c002265c49dea70518f' 
  AND token = 'tM3sC0GEcal3VzQIZhkcM+HMuXAN4pkysbOrcJVLkzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}