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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d5181a75e3428925d949229eda91b9300e7b8e6f91b6f88a298be90027dc1e7' 
  AND token = 't0NZAdwko/rROcE0AIiKd/baghpfcVj96Bx6PovNWCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}