SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '873cb0ce6afbbf1fe6ebe20f44087029012065fdb7d5def1165f31b771ceecad' 
  AND token = '2EVI6EPxRSPKH1UF/1hoqpXuXC2S2alF6SvPYPv7rlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}