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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '046b3ae321d9aa5a3697d76d90254362843cb05b8220e15bbbf706bf424b25c6' 
  AND token = 'QiyJHEDtIsheX5xhQFg+RlRi+8tvCodRXzIHA8R5PNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}